Primary Antibody Matched Pairs
Biotium Perforin-1 (Pore Forming Protein) (Apoptosis Marker)(PRF1/2467), Biotin conjugate, 0.1mg/mL
Perforin is a pore-forming protein that leads to osmotic lysis of the target cells and subsequently enables granzymes to enter the target cells and activate apoptosis. Perforin has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. It is one of the main cytolytic proteins of cytolytic granules, and is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. The expression of perforin is reportedly upregulated in activated CD8 T-cells, natural killer cells and some CD4 T-cells. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjug
ABclonal Technology GSTO1 Rabbit pAb
The protein encoded by this gene is an omega class glutathione S-transferase (GST) with glutathione-dependent thiol transferase and dehydroascorbate reductase activities. GSTs are involved in the metabolism of xenobiotics and carcinogens. The encoded protein acts as a homodimer and is found in the cytoplasm. Three transcript variants encoding different isoforms have been found for this gene.
Medchemexpress LLC Recombinant human aldo-keto reductase AKR1C2, His-tagged | >90.0% | 50 UG
Recombinant human AKR1C2 protein, His-tagged, expressed in E. coli and supplied lyophilized for research use. The enzyme reduces ketosteroids using NADH/NADPH and is characterized for activity, purity, and storage stability.
- Supplied as 50 μg lyophilized protein.
- N-terminal 6xHis tag for purification and detection.
- Expressed in E. coli expression system.
- Purity >90% by reducing SDS-PAGE.
- Approximate molecular weight 38 kDa.
- Specific activity 54.55 pmol/min/μg (S-1-indanol, NADP+).
- Lyophilized from 50 mM Tris-HCl, 300 mM NaCl, pH 7.4; store -20°C.
- After reconstitution, stable at 4°C for 1 week or -20°C for longer with carrier protein.
Biotium Perforin-1 (Pore Forming Protein) (Apoptosis Marker)(PRF1/2467), 0.2mg/mL
Perforin is a pore-forming protein that leads to osmotic lysis of the target cells and subsequently enables granzymes to enter the target cells and activate apoptosis. Perforin has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. It is one of the main cytolytic proteins of cytolytic granules, and is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. The expression of perforin is reportedly upregulated in activated CD8 T-cells, natural killer cells and some CD4 T-cells. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjug
Biotium Carboxypeptidase A1 / CPA1 (Pancreatic Cancer Marker)(CPA1/2713), 1mg/mL
Carboxypeptidase A1 (CPA1) is a secreted zinc metalloprotease that is highly expressed in pancreatic tissue. It catalyzes the release of C-terminal amino acids from a variety of proteins, thereby playing a key role in protein digestion and degradation. Human pancreatic procarboxypeptidase A exists as three different active forms, two of which are carboxypeptidase A1 (CPA1) and carboxypeptidase A2 (CPA2). Abnormal levels of CPA1 are associated with pancreatic cancer, suggesting a possible role in either tumor progression or tumor suppression events. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Miltenyi Biotec, Inc. CD55 (DAF)-APC, human, REAL510, 30 tests
Identification and enumeration of CD55 (DAF)+ cells by flow cytometry.
This product is subject to the following: Miltenyi Biotec, Inc. Terms and Conditions of Sale For Products and Services
Sigma Aldrich Fine Chemicals Biosciences DT Diaphorase NQO1 human l1MG
DT Diaphorase NQO1 human l1MG
Biotium RAD51 (Prognostic and Response to Chemotherapy Marker)(RAD51/2765), 0.2mg/mL
RAD51 is one of the key factors of DNA repair by homologous recombination and has been shown to have anti-apoptotic activity in tumor cells. RAD51 protein interacts with a variety of tumor suppressor proteins including p53, BRCA1 and BRCA2. Elevated expression of RAD51 enhances radio-resistance of human tumor cells. Overexpression of RAD51 protein in tumor cells renders them resistant against cytotoxic drugs like Cisplatin. RAD51 interacts with BRCA1 and BRCA2 to influence subcellular localization and cellular response to DNA damage. BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis from deregulation of RAD51. High-level expression of RAD51 has been observed in a variety of human malignancies. RAD51 overexpression correlates with histological grading of the tumor in invasive ductal mammary carcinoma. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightnes
ABclonal Technology CRYZ Rabbit pAb
Crystallins are separated into two classes taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist.
Biotium CD79b (B-Cell Marker) (IGB/1844), CF568 conjugate, 0.1mg/mL
CD79 (also designated Ig α/Igβ) is a heterodimer composed of α chains, designated CD79A or MB-1, andβ chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-spe
Medchemexpress LLC S100A9 Human His 10ug
S100A9 Protein, Human (His) is a recombinant fragment of the human S100A9 calcium-binding protein supplied lyophilized for research use. The protein contains an N-terminal 6xHis affinity tag, is expressed in Escherichia coli, and is provided with recommended formulation and storage guidance for biochemical and immunological assays.
- Recombinant human S100A9 with N-terminal His tag.
- High purity (>95%) as determined by reducing SDS-PAGE.
- Supplied lyophilized with stabilizers to support storage.
- Suitable for biochemical and immunological research applications.
- Recommended reconstitution at 100 μg/mL or higher and aliquot storage at -20°C/-80°C.
Biotium Cytokeratin 5 (KRT5) (Basal, Myoepithelial & Mesothelial Cell Marker)(KRT5/3594), Biotin conjugate, 0.1mg/mL
This MAb recognizes a protein of 58 kDa, which is identified as Cytokeratin 5 (KRT5). This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Antibodies to KRT5 identify basal cells of squamous and glandular epithelia, myoepithelia, and mesothelium. Anti-cytokeratin 5 has been reported useful in the differential diagnosis of metastatic carcinoma in the pleura versus epithelioid mesothelioma. Almost all squamous cell carcinomas, half of transitional carcinomas, and many undifferentiated large cell carcinomas express. Anti-KRT5, along with anti-p63, affords a high sensitivity and specificity for squamous differentiation. Myoepithelial cells of the breast, glandular epithelia, and basal cells of the prostate are labeled with anti-KRT5. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue f
AFG BIOSCIENCE LLC LTBR Antibody, HRP conjugated, 100ug
Aliases: Tumor necrosis factor receptor superfamily member 3 (Lymphotoxin-beta receptor) (Tumor necrosis factor C receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor receptor type III) (TNF-RIII) (TNFR-III), LTBR, D12S370 TNFCR TNFR3 TNFRSF3
Human GLA ELISA Pair Set 15PP (Sino Biological)
Each vial contains 455 ng of recombinant Human alpha-Galactosidase A / GLA. Reconstitute with 1 mL dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in dilution buffer, and a high standard of 13000 pg/mL is recommended.
Sino Biological Recombinant Human IL-12 R beta 1/IL12RB1 Protein (ECD, His Tag), Endotoxin-Free
A DNA sequence encoding the human IL12RB1 isoform 1 (NP_005526.1) extracellular domain (Met1-Glu540) was expressed fused with a polyhistidine tag at the C-terminus.